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Compound reference

MOTS-c: CAS number, formula, molecular weight and sequence

MOTS-c (Mitochondrial-derived peptide MOTS-c) is a mitochondrial-derived 16-residue peptide, CAS 1627580-64-6, molecular formula C101H152N28O22S2, average molecular weight 2174.6 g/mol.

For Laboratory Research Use Only. Not For Human Consumption.

Chemical data

Name
MOTS-c
Synonyms
Mitochondrial-derived peptide MOTS-c · H-MRWQEMGYIFYPRKLR-OH
CAS number
1627580-64-6
Molecular formula
C101H152N28O22S2
Average molecular weight
2174.6 g/mol
Monoisotopic mass
2173.1077 Da
Residues
16
Class
Mitochondrial-derived 16-residue peptide
PubChem CID
146675088
Form supplied
Lyophilized powder
Purity specification
≥98% (HPLC)
Storage
Store lyophilized at -20°C; protect from light

Sequence

MRWQEMGYIFYPRKLR

Linear unmodified 16-residue peptide, free termini; encoded in the mitochondrial 12S rRNA region (UniProt A0A0C5B5G6, MOTSC_HUMAN).

MOTS-c molarity calculator

Pre-filled with the average molecular weight above. Change it if your lot is a salt form.

g/mol
mg
mL

Uses the formula weight you enter. For salt forms (acetate, TFA) use the salt's weight, and correct for net peptide content from the lot's certificate where it is reported.

Result

1.15 mM

2.5 mg/mL

References

Publications characterising this compound. Neupeptides makes no representation as to the findings, methods or applicability of the work below. The list is bibliographic and is not a claim about any product.

  1. Kim KH, et al. The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress. Cell Metab. 2018. PMID 29983246 · doi:10.1016/j.cmet.2018.06.008

Questions

MOTS-c FAQ

The CAS registry number of MOTS-c is 1627580-64-6.

MOTS-c has an average molecular weight of 2174.6 g/mol and a monoisotopic mass of 2173.1077 Da, molecular formula C101H152N28O22S2. Salt forms such as acetate weigh more; the Certificate of Analysis states the form of each lot.

MOTS-c has 16 residues: MRWQEMGYIFYPRKLR. Linear unmodified 16-residue peptide, free termini; encoded in the mitochondrial 12S rRNA region (UniProt A0A0C5B5G6, MOTSC_HUMAN).

Neupeptides supplies MOTS-c as a lyophilized powder in a sealed vial, for laboratory research use only. Storage: Store lyophilized at -20°C; protect from light. Each lot has a Certificate of Analysis, linked from the QR code on the box.