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Compound reference

Semax: CAS number, formula, molecular weight and sequence

Semax (ACTH (4-7), Pro-Gly-Pro-) is a synthetic heptapeptide (ACTH(4-7)-Pro-Gly-Pro analogue), CAS 80714-61-0, molecular formula C37H51N9O10S, average molecular weight 813.9 g/mol.

For Laboratory Research Use Only. Not For Human Consumption.

Chemical data

Name
Semax
Synonyms
ACTH (4-7), Pro-Gly-Pro- · MEHFPGP · Met-Glu-His-Phe-Pro-Gly-Pro
CAS number
80714-61-0
Molecular formula
C37H51N9O10S
Average molecular weight
813.9 g/mol
Monoisotopic mass
813.3480 Da
Residues
7
Class
Synthetic heptapeptide (ACTH(4-7)-Pro-Gly-Pro analogue)
PubChem CID
9811102
Form supplied
Lyophilized powder
Purity specification
≥98% (HPLC)
Storage
Store lyophilized at -20°C; protect from light

Sequence

MEHFPGP

H-Met-Glu-His-Phe-Pro-Gly-Pro-OH: ACTH(4-7) (MEHF) extended with Pro-Gly-Pro; free termini, unmodified.

Semax molarity calculator

Pre-filled with the average molecular weight above. Change it if your lot is a salt form.

g/mol
mg
mL

Uses the formula weight you enter. For salt forms (acetate, TFA) use the salt's weight, and correct for net peptide content from the lot's certificate where it is reported.

Result

3.072 mM

2.5 mg/mL

References

Publications characterising this compound. Neupeptides makes no representation as to the findings, methods or applicability of the work below. The list is bibliographic and is not a claim about any product.

  1. Magrì A, et al. Influence of the N-terminus acetylation of Semax, a synthetic analog of ACTH(4-10), on copper(II) and zinc(II) coordination and biological properties. J Inorg Biochem. 2016. PMID 27586814 · doi:10.1016/j.jinorgbio.2016.08.013
  2. Dolotov OV, et al. Semax, an analogue of adrenocorticotropin (4-10), binds specifically and increases levels of brain-derived neurotrophic factor protein in rat basal forebrain. J Neurochem. 2006. PMID 16635254 · doi:10.1111/j.1471-4159.2006.03658.x

Questions

Semax FAQ

The CAS registry number of Semax is 80714-61-0.

Semax has an average molecular weight of 813.9 g/mol and a monoisotopic mass of 813.3480 Da, molecular formula C37H51N9O10S. Salt forms such as acetate weigh more; the Certificate of Analysis states the form of each lot.

Semax has 7 residues: MEHFPGP. H-Met-Glu-His-Phe-Pro-Gly-Pro-OH: ACTH(4-7) (MEHF) extended with Pro-Gly-Pro; free termini, unmodified.

Neupeptides supplies Semax as a lyophilized powder in a sealed vial, for laboratory research use only. Storage: Store lyophilized at -20°C; protect from light. Each lot has a Certificate of Analysis, linked from the QR code on the box.