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Compound reference

LL-37: CAS number, formula, molecular weight and sequence

LL-37 (Ropocamptide) is a human cathelicidin-derived 37-residue cationic antimicrobial peptide, CAS 154947-66-7, molecular formula C205H340N60O53, average molecular weight 4493 g/mol.

For Laboratory Research Use Only. Not For Human Consumption.

Chemical data

Name
LL-37
Synonyms
Ropocamptide · Cathelicidin LL-37
CAS number
154947-66-7
Molecular formula
C205H340N60O53
Average molecular weight
4493 g/mol
Monoisotopic mass
4490.5754 Da
Residues
37
Class
Human cathelicidin-derived 37-residue cationic antimicrobial peptide
PubChem CID
16198951
Form supplied
Lyophilized powder
Purity specification
≥98% (HPLC)
Storage
Store lyophilized at -20°C; protect from light

Sequence

LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES

Linear unmodified 37-residue peptide, free termini; residues 134-170 of human cathelicidin antimicrobial peptide precursor CAMP/hCAP-18 (UniProt P49913).

LL-37 molarity calculator

Pre-filled with the average molecular weight above. Change it if your lot is a salt form.

g/mol
mg
mL

Uses the formula weight you enter. For salt forms (acetate, TFA) use the salt's weight, and correct for net peptide content from the lot's certificate where it is reported.

Result

556.421 µM

2.5 mg/mL

References

Publications characterising this compound. Neupeptides makes no representation as to the findings, methods or applicability of the work below. The list is bibliographic and is not a claim about any product.

  1. Gudmundsson GH, et al. The human gene FALL39 and processing of the cathelin precursor to the antibacterial peptide LL-37 in granulocytes. Eur J Biochem. 1996. PMID 8681941 · doi:10.1111/j.1432-1033.1996.0325z.x
  2. Porcelli F, et al. NMR structure of the cathelicidin-derived human antimicrobial peptide LL-37 in dodecylphosphocholine micelles. Biochemistry. 2008. PMID 18439024 · doi:10.1021/bi702036s
  3. Sancho-Vaello E, et al. The structure of the antimicrobial human cathelicidin LL-37 shows oligomerization and channel formation in the presence of membrane mimics. Sci Rep. 2020. PMID 33060695 · doi:10.1038/s41598-020-74401-5

Questions

LL-37 FAQ

The CAS registry number of LL-37 is 154947-66-7.

LL-37 has an average molecular weight of 4493 g/mol and a monoisotopic mass of 4490.5754 Da, molecular formula C205H340N60O53. Salt forms such as acetate weigh more; the Certificate of Analysis states the form of each lot.

LL-37 has 37 residues: LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES. Linear unmodified 37-residue peptide, free termini; residues 134-170 of human cathelicidin antimicrobial peptide precursor CAMP/hCAP-18 (UniProt P49913).

Neupeptides supplies LL-37 as a lyophilized powder in a sealed vial, for laboratory research use only. Storage: Store lyophilized at -20°C; protect from light. Each lot has a Certificate of Analysis, linked from the QR code on the box.