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Compound reference

Thymosin alpha-1: CAS number, formula, molecular weight and sequence

Thymosin alpha-1 (Thymalfasin) is an N-acetylated 28-residue peptide (prothymosin alpha fragment), CAS 62304-98-7, molecular formula C129H215N33O55, average molecular weight 3108.3 g/mol.

For Laboratory Research Use Only. Not For Human Consumption.

Chemical data

Name
Thymosin alpha-1
Synonyms
Thymalfasin · Thymosin alpha 1 · alpha1-Thymosin
CAS number
62304-98-769521-94-4 also appears in chemical registries for the same peptide.
Molecular formula
C129H215N33O55
Average molecular weight
3108.3 g/mol
Monoisotopic mass
3106.5041 Da
Residues
28
Class
N-acetylated 28-residue peptide (prothymosin alpha fragment)
PubChem CID
16130571
Form supplied
Lyophilized powder
Purity specification
≥98% (HPLC)
Storage
Store lyophilized at -20°C; protect from light

Sequence

SDAAVDTSSEITTKDLKEKKEVVEEAEN

N-acetyl-Ser1; free C-terminal Asn28 acid; identical to residues 2-29 of human prothymosin alpha (UniProt P06454).

Thymosin alpha-1 molarity calculator

Pre-filled with the average molecular weight above. Change it if your lot is a salt form.

g/mol
mg
mL

Uses the formula weight you enter. For salt forms (acetate, TFA) use the salt's weight, and correct for net peptide content from the lot's certificate where it is reported.

Result

804.298 µM

2.5 mg/mL

References

Publications characterising this compound. Neupeptides makes no representation as to the findings, methods or applicability of the work below. The list is bibliographic and is not a claim about any product.

  1. Goldstein AL, et al. Thymosin alpha1: isolation and sequence analysis of an immunologically active thymic polypeptide. Proc Natl Acad Sci U S A. 1977. PMID 265536 · doi:10.1073/pnas.74.2.725
  2. Elizondo-Riojas MA, et al. NMR structure of human thymosin alpha-1. Biochem Biophys Res Commun. 2011. PMID 22115779 · doi:10.1016/j.bbrc.2011.11.041
  3. Wang SS, et al. Automated solid phase synthesis of thymosin alpha 1. Int J Pept Protein Res. 1980. PMID 7358454 · doi:10.1111/j.1399-3011.1980.tb02543.x

Questions

Thymosin alpha-1 FAQ

The CAS registry number of Thymosin alpha-1 is 62304-98-7. 69521-94-4 also appears in chemical registries for the same peptide.

Thymosin alpha-1 has an average molecular weight of 3108.3 g/mol and a monoisotopic mass of 3106.5041 Da, molecular formula C129H215N33O55. Salt forms such as acetate weigh more; the Certificate of Analysis states the form of each lot.

Thymosin alpha-1 has 28 residues: SDAAVDTSSEITTKDLKEKKEVVEEAEN. N-acetyl-Ser1; free C-terminal Asn28 acid; identical to residues 2-29 of human prothymosin alpha (UniProt P06454).

Neupeptides supplies Thymosin alpha-1 as a lyophilized powder in a sealed vial, for laboratory research use only. Storage: Store lyophilized at -20°C; protect from light. Each lot has a Certificate of Analysis, linked from the QR code on the box.